Bio Monthly (Mar 2025): Bio V1 Launches, Agentic Science Hackathon, Fungal Biotech, SpineDAO Shines

Highlights:

• Bio V1 went live Tuesday on Solana & Base, kicking off the first ever community-curated BioDAOs. Over 2.5M BIO was locked in the first day and over 3.2M BIO curated so far. V1 introduces a permissionless launchpad, an automated liquidity and incentives engine, and BioAgents. Dive into Bio V1 on the Bio App.
• The Bio x AI Hackathon, sponsored by the Solana Foundation, elizaOS, Prime Intellect, & OriginTrail is kicking off next week in Berlin, offering $125K+ in prizes for building scientific AI agents. The hackathon is fully virtual and global - apply here.
• Curetopia raised $1.77M from over 1,000 participants & launched their $CURES token on Solana to fund decentralized trials and drug repurposing for rare diseases. They also successfully conducted a yeast-powered test-flight screen uncovering a potential treatment for AARS2 deficiency, with a provisional patent filing underway.
• MycoDAO was announced as a new BioDAO advancing biotech breakthroughs using mycelium and mushrooms. They launched their curation phase with 817K+ BIO curated on the Bio Launchpad so far.
• SpineDAO hit its 2M+ BIO Curation limit in a matter of hours, showing the massive pent-up demand for the BioDAO led by leading spinal surgeons!
• Recent scientific progress in the Bio Network includes VitaDAO-backed Turn Bio acquired Harvard’s microvesicle tech, autophagy-enhancing compounds, biotech breakthroughs in enzyme-treated hemp fibers and hair loss studies.

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💻 Dev Updates

• Bio V1 was deployed on both Solana and Base. We hosted an event outlining how attendees can lock BIO for pre-sale tokens for MycoDAO, SpineDAO, and ReflexDAO. Check out our breakdown detailing launchpad mechanics, rapid research funding, value flows, BioAgents & our live community discussion.
• We've launched our Bio x AI site, dedicated to accelerating life sciences with a fleet of autonomous BioAgents. BioAgents are AI-powered research assistants that automate core scientific tasks, including data analysis, hypothesis testing, experimental design, submission to labs & IP claims. Join our BioAgent Builders Telegram to learn more.
• BioAgents have joined Olas Accelerator's $1 million grant program focusing on accelerating scientific breakthroughs by digesting literature, generating hypotheses, designing experiments, and creating IP-NFTs.
• Messari Research covered how Bio V1 diversifies revenue across asset management, fundraising fees, liquidity provision, and agent services, shifting from a treasury-based to a sum-of-parts value model.
• Vending Machine modeled BIO Protocol's scientific value generation via 4 proposed components: value origination through Bio Launchpad-funded BioDAOs and IPTs, value creation from research breakthroughs, value accrual via tokenized IP and governance, and value distribution through long-term BIO staking - Learn more.
• New Bio Protocol technical docs went live, covering smart contract architecture, network concepts, quick start guides and more!

💡New BioDAOs

• SpineDAO are launching their $SPINE token on Solana through the Bio V1 launchpad, starting with their curation phase hitting the 2.25M BIO curation limit within hours of Bio V1's launch. Next up, they enter the $SPINE auction funding phase, where successful funding will grant pre-sale $SPINE tokens to BIO curators. They also shared a progress update highlighting website enhancements, $SPINE token curation, product development for faster patient access, global outreach by key DAO figures at the AAOS annual meeting & more.
• MycoDAO was announced as a new BioDAO advancing biotech breakthroughs using mycelium and mushrooms. Myco's decentralized platform for open fungal data and equipment accelerates the discovery of fungi-based medicines, materials, and biotech. They launched their curation phase with 817K+ BIO curated on the Bio Launchpad, allowing users to acquire $MYCO tokens at a discounted price using BIO, $SOL, or $BTC, followed by an auction. Myco's first project, Project Oyster uses mycelium to tackle the U.S. sewage crisis and nitrogen pollution.
• ReflexDAO started the whitelist phase of curation, reaching 114K+ in BIO so far on the Bio Launchpad. They also released their litepaper and one-pager outlining how they are creating a decentralized platform using wearables to monitor the autonomic nervous system, detect diseases early, and empower data ownership.
• Curetopia raised $1.77M from over 1,000 participants & launched their $CURES token on Solana. The DAO announced they had uncovered potential treatments to AARS2, paving the way to the first DeSci-native disease cure. Curetopia was featured in a DeSci case study & talked with Solana Skyline to discuss its plans at advance rare disease treatments.
• Quantum Biology DAO bridged QBIO to Solana, are in the final stages of setting up their lab in Los Angeles, presented at the Quantum Biology Gordon Research Conference, and introduced their new head of ops.

🌐 Network Updates

• VitaDAO's VitaLabs Season 2 started - Apply to get your longevity research funded. VitaDAO-backed Turn Bio acquired Vesigen’s Harvard-developed microvesicle technology enhancing precision in mRNA-based epigenetic reprogramming therapies. Their VITA-FAST proposal to invest $135K and initiate the next steps of the project, to identify a lead candidate, define targets, and file IP was approved. VitaRNA also progressed with their CRO shipping RNA from various tissues to track Artan-102 delivery, and doing potency testing, with results soon. They also developed the Longevist AI Agent (LAIA) to autonomously curate longevity preprints and collaborate with VitaLabs.
• HairDAO, operating the largest human tissue lab in the U.S., took 475 photos across 3 donors in one of their most promising in-house studies across 60 culture wells, including siRNA testing, analyzing 25 hair follicles with RNA sequencing & testing 26 others. They are also conducting parallel studies on treatments like Twist inhibitors, optimized topical dutasteride, and TRH formulas in multiple countries. HairDAO also allocated $1 million USD and $3 million in $HAIR tokens to expand their full-time team & already hired their new CMO. They also launched the "Hair Rewards" program, offering rewards of up to 30% in $HAIR tokens.
• ValleyDAO shared the first Hempy data drop, including a breakthrough in softening hemp fibers using enzyme treatments. Their Hempy project unveiled SnoopHaze, an AI-woven, fireproof, smokable hemp textile with self-lighting features, and CBD face mask functionality. Their portfolio organization, SiriusBio, secured a contract for metabolic engineering. ValleyDAO also finished training their Phlo Research Co-Pilot, using AI to accelerate research & review literature - see demo. The DAO also announced hiring for an Entrepreneur in Residence, initiated Hempy-branded hemp clothing merch, and kicked off their Proof of DeSci series.
• PsyDAO's BeeARD project is hosting an AI x Science Hackathon with Google on April 14 in Wroclaw, Poland, to build AI-powered systems generating scientific hypotheses, with mentorship, prizes, and networking opportunities - Apply by April 6, 2025. BeeARD AI is also initiating AI-driven discovery starting with knowledge graphs and longevity in collaboration with Coordination Network & launched a new website & docs. PsyDAO also launched a staking program, offering up to 6154.52% APY for staking $PSY to earn $BeeARD.
• Pump Science launched their ecommerce store, introducing Urolithin A as the first product available for pre-order, including discounts, offering the next 25 orders an airdrop for approximately 45% off & the next 10 buyers a bonus of $DRUGS - Preorder here. They also previewed "F1y Racing," an experiment featuring flies racing in test tubes. Additionally, Torii Security audited their protocol updates including sharing LP fees with the drug devs, slower bonding curve fees for sniper protection, and automating airdrops. They also outlined the process of proposing compound ideas - Submit here.
• Cerebrum DAO minted their third IP-NFT, "Transfidelity for Protein Stability," and signed the sponsored research agreement for the project targeting neurodegenerative diseases by improving protein translation accuracy to prevent toxic aggregates. They also hosted an event in Bangkok, offering an afternoon of networking, local brews, and canapés for DeSci enthusiasts, founders, VCs, and researchers.
• AthenaDAO's funded research was featured in TIME, suggesting that ovarian tissue cryopreservation and transplantation could delay menopause by 10–47 years & improve health outcomes, and has led to the launch of a reproductive longevity startup. They also hosted a DeSci community day with ArkHaus in Istanbul, exploring how DeSci is transforming scientific funding, transparency, and collaboration, featuring panels, talks, and networking. Further, their Fertility 101 Course participants are minting NFTs for access to Season 2 of the course.
• Molecule co-hosted a AB4AD Community Call with Daniel Bar and VitaDAO discussing the latest project updates. They also posted a blog post exploring how DeSci can break down the silos of academia, fostering interdisciplinary collaboration, innovation, and reviving the polymathic legacy of figures like da Vinci and Curie. They also recorded a new podcast episode with Graham Pechenik on how patents and IP shape the future of psychedelic medicine like LSD and psilocybin.

🧪 Bio Community Updates

• The Bio x AI Hackathon is kicking off next week in Berlin April 8-10 with the Solana Foundation, elizaOS, Prime Intellect, & OriginTrail as sponsors offering $125K+ in prizes for creating BioAgents to automate scientific processes. Here are some ideas for hackathon challenges, such as tools to detecting null results, new scientific publication tooling and more. Learn more & Apply here.
• Bio is hosting the DeSci Summit Dubai 2025 with VitaDAO on April 29 at the Museum of the Future in Dubai, for keynote speeches, workshops, and discussions on DeSci, alongside networking and an exclusive VIP dinner. RSVP here or Apply to Speak.
• The Block covers Bio V1, focusing on how it helps global communities fund and co-own biotech innovations while cutting costs.
• The 8-week DeSci Edu Course, initiated by Molecule and Bio, welcomed the first participants, aiming to deepen their DeSci knowledge & involvement.
• CoinGecko explored whether web3 can revolutionize science through DeSci, discussing its ethos, existing projects, and current challenges.
• The second episode of the DeSci Pilled Podcast went live, focused on the future of DeSci, ethical challenges in food, pharma, biotech & more, featuring Molecule & Solana Skyline. 6 new episodes are coming soon with the 3rd episode of DeSci Pilled featuring Andrew Verbinnen from HairDAO.
• Paul Kohlhaas, co-founder of Bio Protocol, told the origin story of Curetopia, from cold-emailing Ethan Perlstein in 2019, inspired by his open drug research talk, igniting a connection that lay dormant until 2021, when Ethan suggested a rare disease collaboration.

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